Maryam Noorshahi; Samaneh Koneshloo; Mehdi Hedayati; Mostafa Baranchi; Nafiseh AminolEslam; Javad Nemati
Volume 21, Issue 6 , January and February 2015, , Pages 1113-1122
Abstract
Background and Purpose: Mechanical tension induced by resistance exercise can stimulate tension-sensitive cytoskeletal proteins. Also, resistance exercise can induce inflammatory factors. Therefore, the aim of this study was to investigate the changes of inflammatory and hypertrophic markers and their ...
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Background and Purpose: Mechanical tension induced by resistance exercise can stimulate tension-sensitive cytoskeletal proteins. Also, resistance exercise can induce inflammatory factors. Therefore, the aim of this study was to investigate the changes of inflammatory and hypertrophic markers and their association with a single bout of resistance exercise in male rats.
Materials and Methods: Twelve male Wistar rats, three months of age, were randomly assigned into control and experimental groups. Resistance exercise protocol (to climb up a one-meter ladder, 3 sets, 10 repetitions in each set, at 50%, 75% and 100% of their own body weight) was performed. The control group did not perform any exercise activity. Twelve hours after the last session of exercise, rats (both control and experimental) were anesthetized with a mixture of ketamine/xylazine. Blood samples were taken directly from the heart; their Soleus muscles were extracted. Vinculin levels in muscle tissue after homogenation and IL-17 levels in sera were measured using ELISA method. Creatine kinase levels were measured by enzymatic colorimetric methods. Independent t-test and Pearson correlation coefficient were used. A significance level of α= 0.05 was considered.
Results: There was no significant diferences between control and experimental groups in vinculin, IL-17 and creatine kinase levels (p>0.05). Nevertheless, there was a significant negative corrolation between vinculin and IL-17 (r=-0.93, p=0.01).
Conclusion: A single bout of resistance training can lead to a change in vinculin, IL-17 and creatine kinase levels. Interaction between inflammatory and hypertrophic markers (especially vinculin and IL-17) probably has a role in adaptations induced by resistance training.
Hamid Aghaalinejad; Reza Gharakhanloo; Mostafa Baranchi
Volume 21, Issue 5 , September and October 2014, , Pages 786-796
Abstract
Background and purpose: Every type of exercises could lead to different immune responses in human body. The purpose of this study was to compare the acute effects of endurance exercises (EE), resistance exercises (RE) and concurrent exercises (CE) on serum interleukin-17 (IL-17) concentrations and number ...
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Background and purpose: Every type of exercises could lead to different immune responses in human body. The purpose of this study was to compare the acute effects of endurance exercises (EE), resistance exercises (RE) and concurrent exercises (CE) on serum interleukin-17 (IL-17) concentrations and number of lymphocytes, monocytes, and neutrophils in active men.
Materials and Methods: Twenty healthy young and active men (Age: 21.69±2.66; BMI: 21.92±1.89; Fat%: 14.49±3.05) voluntarily participated in this study and randomly were assigned into three groups: EE (n=7), RE (n=6) and CE (n=7). Subjects performed special exercise protocol for each group consisted of 45 minute. IL-17 serum concentrations were measured by ELISA method and so numbers of some classes of leukocytes were computed (Pre, immediate and 1 hour post-exercises). Data were analyzed using Repeated-Measures analysis of variance, One-Way ANOVA and Tukey post-hoc and Paird T-test at the significance level of α=0.05
Results: Changes in the serum levels of interleukin-17 was significantly different between groups immediately after exercise and 1 h post-exercise. Also, lymphocytes and neutrophils numbers 1 h post-exercise and monocytes and neutrophils numbers, 1 h post-exercise compared to basal levels were significantly different between three exercise groups, respectively (p